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Highlights

  • Exploring hidden hearing loss

    The degeneration of neurons in the cochlea underlies the hearing difficulties reported by adults who have normal audiograms when their hearing is tested.

    Maggie E Zink, Leslie Zhen ... Aravindakshan Parthasarathy
    Research Article

  • Responding to retinal damage

    Damage to photoreceptors in the retina does not lead to the recruitment of neutrophils, despite the activation of microglial cells.

    Derek Power, Justin Elstrott, Jesse Schallek
    Research Article

  • New publishing agreements

    Agreements between eLife and research institutions will support a more equitable and sustainable scientific publishing system.

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Latest research

    1. Cell Biology

    CCDC32 stabilizes clathrin-coated pits and drives their invagination

    Ziyan Yang, Changsong Yang ... Zhiming Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progression

    Jimena Druker, Hao Jiang ... Angus I Lamond
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Immunology and Inflammation

    Xcr1+ type 1 conventional dendritic cells are essential mediators for atherosclerosis progression

    Tianhan Li, Liaoxun Lu ... Lichen Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Alternatives to Friction Coefficient: Fine Touch Perception Correlates with Frictional Instabilities

    Maryanne Derkaloustian, Pushpita Bhattacharyya ... Charles B Dhong
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Sub-type specific connectivity between CA3 pyramidal neurons may underlie their sequential activation during sharp waves

    Rosanna P Sammons, Stefano Masserini ... Dietmar Schmitz
    The asymmetric connectivity between thorny and athorny pyramidal neurons in the CA3 region is the key in maintaining the separation of peak firing during sharp wave events.
    1. Evolutionary Biology

    Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D geometric morphometrics reveals wide-gauge posture as an exaptation for gigantism

    Adrián Páramo, Pedro Mocho ... Francisco Ortega
    Wide-gauge posture in the limb skeleton of Titanosauriformes is an exaptation to gigantism, as it is not correlated with body size in deeply branching titanosaurs.
    1. Structural Biology and Molecular Biophysics

    DIRseq: a method for predicting drug-interacting residues of intrinsically disordered proteins from sequences

    Matthew MacAinsh, Sanbo Qin, Huan-Xiang Zhou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    A SHERLOCK toolbox for eco-epidemiological surveillance of African trypanosomes in domestic pigs from Western Africa

    Roger-Junior Eloiflin, Elena Pérez-Antón ... Brice Rotureau
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    MCAK Recognizes the Nucleotide-Dependent Feature at Growing Microtubule Ends

    Wei Chen, Yin-Long Song ... Xin Liang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Cancer Biology

    An Evaluation of the Tumor Microenvironment through CALR, IL1R1, IFNB1, and IFNG to Assess Prognosis and Immunotherapy Response in Bladder Cancer Patients

    Lilong Liu, Zhenghao Liu ... Zheng Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
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Magazine

    1. Evolutionary Biology

    Microfossils: Mimicking early life-forms in the lab

    Maarten Lubbers, Dennis Claessen
    1. Cell Biology

    Membrane Biology: Nothing can replace polyunsaturated lipids

    Sofia Rodriguez-Gallardo, Takeshi Harayama
    1. Neuroscience

    Behavioral Neuroscience: The consequences of stress on the brain and fear

    Nicole C Ferrara, Sydney Trask
    1. Developmental Biology
    2. Neuroscience

    Ribbon Synapses: Taking the tube to the basal pole of hair cells

    Satish R Ghimire, Thomas M Coate
    1. Cell Biology

    Lymphatic System: Closing in on pacemaker cells

    Pin-Ji Lei, Timothy P Padera
    1. Plant Biology

    Symbiosis: How plants pick their friends

    Estelle Grundy, Michael Udvardi
    1. Evolutionary Biology

    Evolutionary Biology: Embracing the complexity of cooperation

    Benjamin Allen
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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